‘Girl, Interrupted’ Cast Then & Now: Photos Of Angelina Jolie & More After 22 Years

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January 14, 2022 2:37PM EST

‘Girl, Interrupted’ won Angelina Jolie an Oscar over two decades ago! See photos of the movie’s cast then and now.

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‘Girl, Interrupted’ Cast: Angelina Jolie

‘Girl, Interrupted’ Cast: Angelina Jolie — It’s hard to believe ‘Girl,Interrupted’ hit theaters all the way back on January 14, 2000! The heartbreaking drama not only shed a light on the importance of mental healthcare — but also brought Angelina Jolie an Oscar for Best Supporting Actress. Based on Susanna Kaysen’s 1993 memoir of the same name, the film tells the story of a teenage girl being place in a mental institution in 1967 after attempting suicide. Angelina, Winona Ryder, Brittany Murphy, Clea DuVall and Elisabeth Moss starred as patients suffering from a range of mental illnesses. Rounding out the cast were Jared Leto, Jeffrey Tambor, Whoopi Goldberg and Vanessa Redgrave.

Angelina’s role as Lisa, a rebellious and manipulative patient, made the young star a household name. She then became a Hollywood icon with blockbusters like ‘Tomb Raider,’ ‘Maleficent’ and Marvel’s ‘Eternals.’ Her romance with her ‘Mr. & Mrs. Smith’ co-star Brad Pitt and their bitter divorce caused her to grab headlines as well. Now the mother of six enjoys directing and giving back, as she is a celebrated humanitarian.

See more photos of the ‘Girl, Interrupted’ cast then and now in our gallery.

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Winona Ryder

Winona Ryder — Winona Ryder starred as the main character Susanna, who is placed in the mental health facility following a suicide attempt.

After disappearing from the spotlight for a few years after her infamous 2001 shoplifting arrest, Winona made a comeback with such hits as ‘Star Trek,’ ‘Black Swan’ and ‘The Ice Man.’ More recently, she’s found a new fan base as Joyce Byers in ‘Stranger Things.’

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Clea DuVall

Clea DuVall — Clea DuVall stole the spotlight as Georgina, the pathological liar who ends up rooming with Susanna.

The versatile actress would go on to star in HBO’s ‘Carnivale’ for two years, before landing a role in Ben Affleck’s ‘Argo,’ earning her and the cast the 2013 SAG Award for Outstanding Performance by a Cast in a Motion Picture. Clea has also appeared in ‘American Horror Story,’ ‘Veep’ and ‘The Handmaid’s Tale.’

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Brittany Murphy

Brittany Murphy — Brittany Murphy broke hearts as Daisy, the sexually abused teen who ends up dying by suicide.

Although Brittany first found fame in 1995’s ‘Clueless,’ she would go on to grab more dramatic roles after winning over critics for ‘Girl, Interrupted.’ She starred in ‘8 Mile’ alongside Eminem and anchored both ‘Riding in Cars with Boys’ and ‘Sin City.’ Sadly, she was found unconscious in her home in 2009 and her cause of death was ruled as pneumonia two months later.

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Elisabeth Moss

Elisabeth Moss — Elisabeth Moss was a newbie on the Hollywood scene when she broke out as Polly ‘Torch’ Clark, the burn victim who suffers from schizophrenia in ‘Girl, Interrupted.’

While the movie was premiering, Elisabeth was also hard at work on ‘The West Wing,’ playing the President’s daughter. She then starred as Peggy Olsen in ‘Mad Men’ and won accolades for the BBC miniseries ‘Top of the Lake.’ An Emmy was then won for her lead role in ‘The Handmaid’s Tale.’

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Jared Leto

Jared Leto — Jared Leto made fans swoon as Susanna’s ex-boyfriend. Toby, who vows to escape to Canada aftet being drafted by the army.

The same year as ‘Girl, Interrupted’ came out, Jared won critical acclaim for his role as a tortured soul in ‘Requiem for a Dream.’ After starting his own successful rock band, 30 Seconds to Mars, the actor would go on to win a Best Supporting Actor Oscar for ‘Dallas Buyers Club.’ More recently, he played Joker in ‘Suicide Squad.’

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Jeffrey Tambor

Jeffrey Tambor — Playing Dr. Melvin Potts, Jeffrey Tambor has regular therapy sessions with Susanna, where he diagnoses her with borderline personality disorder.

Jeffrey’s career included hilarious roles in ‘The Hangover’ trilogy and as the patriarch in ‘Arrested Development.’ He would go on to win two Emmy awards for playing Maura Pfefferman on ‘Transparent.’ However, the actor was let go from the show after he was twice accused of sexual misconduct on set.

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Vanessa Redgrave

Vanessa Redgrave — Vanessa Redgrave had a brief, but memorable performance as Dr. Sonia Wick, the head psychologist of the mental health facility.

The legendary actress, who won an Oscar, two Emmys and a Tony, would go on to receive two more Tony nominations for her Broadway work in ‘Driving Miss Daisy’ and ‘The Year of Magical Thinking.’ Later, she would star in ‘Atonement.’ ‘Letters to Juliet’ and ‘The Butler.’

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Whoopi Goldberg

Whoopi Goldberg — Whoopi Goldberg melted hearts as nurse Valerie, who watches over her troubled patients with love and empathy.

Whoopi would go on to become a member of the EGOT club, being only one of 15 people so far who have won an Emmy, Grammy, Oscar and Tony. And she’s ruled daytime TV since 2007, when she took over the hosting gig of ‘The View.’

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