‘ER’ is one of the longest-running medical drama series. See the iconic cast then and now.
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‘ER’ Cast Transformations — George Clooney & More
![‘ER’ Cast Transformations — George Clooney & More](https://hollywoodlife.com/wp-content/uploads/2021/04/er-cast-then-now-george-clooney.jpg?w=680)
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Julianna Marguiles
![Julianna Marguiles](https://hollywoodlife.com/wp-content/uploads/2021/04/er-cast-then-now-Julianna-Margulies.jpg?w=680)
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Noah Wyle
![Noah Wyle](https://hollywoodlife.com/wp-content/uploads/2021/04/er-cast-then-now-noah-wyle.jpg?w=680)
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Anthony Edwards
![Anthony Edwards](https://hollywoodlife.com/wp-content/uploads/2021/04/er-cast-then-now-anthony-edwards.jpg?w=680)
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Eriq La Salle
![Eriq La Salle](https://hollywoodlife.com/wp-content/uploads/2021/04/er-cast-then-now-Eriq-La-Salle.jpg?w=680)
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Laura Innes
![Laura Innes](https://hollywoodlife.com/wp-content/uploads/2021/04/er-cast-then-now-Laura-Innes.jpg?w=680)
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Sherry Stringfield
![Sherry Stringfield](https://hollywoodlife.com/wp-content/uploads/2021/04/er-cast-then-now-Sherry-Stringfield.jpg?w=680)
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Alex Kingston
![Alex Kingston](https://hollywoodlife.com/wp-content/uploads/2021/04/er-cast-then-now-Alex-Kingston.jpg?w=680)
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Ming-Na Wen
![Ming-Na Wen](https://hollywoodlife.com/wp-content/uploads/2021/04/er-cast-then-now-Ming-Na-Wen.jpg?w=680)
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Yvette Freeman
![Yvette Freeman](https://hollywoodlife.com/wp-content/uploads/2021/04/er-cast-then-now-Yvette-Freeman.jpg?w=680)
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Goran Visnjic
![Goran Visnjic](https://hollywoodlife.com/wp-content/uploads/2021/04/er-cast-then-now-Goran-Visnjic.jpg?w=680)
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Gloria Reuben
![Gloria Reuben](https://hollywoodlife.com/wp-content/uploads/2021/04/er-cast-then-now-Gloria-Reuben.jpg?w=680)
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Maura Tierney
![Maura Tierney](https://hollywoodlife.com/wp-content/uploads/2021/04/er-cast-then-now-Maura-Tierney.jpg?w=680)
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Laura Cerón
![Laura Cerón](https://hollywoodlife.com/wp-content/uploads/2021/04/er-cast-then-now-Laura-Ceron.jpg?w=680)
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Conni Marie Brazelton
![Conni Marie Brazelton](https://hollywoodlife.com/wp-content/uploads/2021/04/er-cast-then-now-Conni-Marie-Brazelton.jpg?w=680)
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Paul McCrane
![Paul McCrane](https://hollywoodlife.com/wp-content/uploads/2021/04/er-cast-then-now-paul-mccrane.jpg?w=680)
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CCH Pounder
![CCH Pounder](https://hollywoodlife.com/wp-content/uploads/2021/04/er-cast-then-now-CCH-Pounder-2.jpg?w=680)