SEE THE CAST THEN AND NOW

ABC’s longest running medical drama is still going strong, but here’s where the original cast is now!

 Meredith Grey: After 17 seasons, she’s still holding a scalpel, leading the team in Seattle.

Ellen Pompeo 

Christina Yang: After 10 seasons with the show, she bowed out to star in new series, like ‘Killing Eve’.

Sandra Oh

Derek Shepard: After being killed off in season 11, he returned in season 17 for a special appearance.

Patrick Dempsey

Izzie Stevens: She’s been off the show since season 6, and no stars on ‘Suits’ and ‘Firefly Lane’.

Katherine Heigl

Miranda Bailey: Like Ellen Pompeo, she’s been with the show every season since it started.

Chandra Wilson

Alex Karev: He left the show in season 16, with his character reuniting with Izzie off-screen.

Justin Chambers

George O’Malley -- He died in season 5, but like Derek, returned to visit Meredith in her coma in season 17.

T.R. Knight