Halle Berry had jost won an Oscar when she got the 2003 cover, but soon after split with her sex addict husband Eric Benet.
Ryan Reynolds landed on the 2010 Sexiest Man Alive cover, remaining coy on his marriage to Scarlett Johansson. The two were not coy soon after, however, when they announced they were splitting.
Nicole Kidman was split from Tom Cruise and had yet to marry Keith Urban when she was on the 2002 cover, but in an interview she claims she was engaged to a man between the split and her marriage, meaning that relationship would go south soon after her aesthetic honor.
Jennifer Aniston was married to a minor actor named Brad Pitt when she made the cover of the 2004 Most Beautiful People issue. A year later, they had split.
Jennifer Lopez scored the latest cover of the Most Beautiful People issue, and soon after split from husband Marc Anthony.
Julia Roberts has had the distinction of scoring both the 1991 and 2000 covers of the Most Beautiful People issue. She split from fiance Kiefer Sutherland in 1992 and long time boyfriend Benjamin Bratt in 2001.
Drew Barrymore had been dating Strokes drummer Fabrizio Moretti for five years when she landed on the 2007 cover, they split soon after.
Cindy Crawford and Richard Gere scored a joint cover in 1993. Sadly, they jointly separated two years later.
Harrison Ford’s twenty year marriage would end soon after he was celebrated at the Sexiest Man Alive in 1998.
Ben Affleck was part of the iconic Bennifer when he wound up the 2002 Sexiest Man Alive. Two years later Jennifer was gone and he was Ben again — until he met current wife Jennifer Garner.
Kate Hudson spend a large part of the late aughties in an on again and off again relationship with Owen Wilson, one that would end for good a year after her 2008 Most Beautiful Person cover.